Development of antithrombotic nanoconjugate blocking integrin α2β1-collagen interactions
نویسندگان
چکیده
منابع مشابه
Development of antithrombotic nanoconjugate blocking integrin α2β1-collagen interactions
An antithrombotic nanoconjugate was designed in which a designed biomimetic peptide LWWNSYY was immobilized to the surface of poly(glycidyl methacrylate) nanoparticles (PGMA NPs). Our previous work has demonstrated LWWNSYY to be an effective inhibitor of integrin α2β1-collagen interaction and subsequent thrombus formation, however its practical application suffered from the formation of cluster...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep26292